Chronic Peripheral Nerve Pain: Relief to Rely on
Bioventus’ peripheral nerve stimulation (PNS) devices target chronic peripheral nerve pain at its source—without drugs used for chronic pain or significantly invasive surgery.
TalisMann is a next-generation permanent PNS system that combines our patented electric field conduction technology with an integrated pulse generator (IPG).
TalisMann is the only permanent PNS IPG system offering:1-4
- Electric Field Conduction Technology
- Purpose-built design for the peripheral nerves
- Highest peak current
- Smallest and lightest external wearable
StimTrial is a temporary system implanted through a minimally invasive procedure that can help determine patient candidacy for a permanent PNS system.
StimRouter is a permanent implantable neuromodulation device indicated for pain management in adults with severe, intractable, chronic pain of peripheral nerve origin.
TalisMann, StimRouter, and StimTrial patients can adjust the stimulation level via an external wearable unit (placed on the skin) or a mobile app.
For more information, including full prescribing information, visit BioventusPNS.
Pain Relief That Targets the Pain Directly in a Patient’s Joints
Osteoarthritis (OA) is the most common cause of knee and hip pain, causing sufferers significant pain while limiting their ability to lead active lives. Bioventus’ joint pain injection therapies are nonsurgical alternatives created to work with the body’s biological processes, providing a natural lubricant into the joint that relieve mild to moderate pain, improves mobility, and helps the patient get back to their normal activities.
Many OA patients find that their synovial joint fluid gets weaker as this chronic disease progresses. By injecting hyaluronic acid directly to affected areas, our therapies are able to restore the lubricating and shock-absorbing properties of joint fluid, which are normally depleted due to OA. Unlike the generalized relief experienced with oral painkillers, precise injection of HA therapy directly into the joint safely relieves pain from osteoarthritis and helps patients get back to their daily lives.
DUROLANE, GELSYN-3 and SUPARTZ FX can be administered right in a doctor’s office. The procedure only takes a few minutes, and most patients experience little or no discomfort during the injection.
For more information about how our joint injection therapies can bring the pain relief and mobility to the patient, including full prescribing information and clinical research, visit OAKneePainRelief.com.
Patient Assistance Program
Bioventus is committed to providing access to SUPARTZ FX, GELSYN-3 and DUROLANE to patients without the financial resources to pay for the treatment by providing Patient Assistance Product at no cost. Learn more
XCELL PRP®: Designed for Precision and Efficiency in Platelet-Rich Plasma (PRP) Preparation
The XCELL PRP system is a benchtop device that processes whole blood to produce high-yield PRP with a 10-minute single-spin cycle.
The system offers leukocyte-rich and leukocyte-poor PRP preparations in one platform. Designed to capture the entire buffy coat, the system is engineered to provide consistent processing results.5
The XCELL PRP system delivers customized treatments from an advanced benchtop processing station with a hand-controlled dial, visit BioventusPRP.com.
References: 1. Bioventus LLC. 510(k) Summary for TalisMann Neuromodulation System (K243678). Prepared: July 2, 2025. 2. Nalu Medical Inc. K233801 – Nalu Wearable Update. Letter from the US Food & Drug Administration; August 23, 2024. 3. Curonix. K233162. Letter from the US Food & Drug Administration; June 20, 2024. 4. Stimwave Technologies Incorporated. K182720. Letter from the US Food & Drug Administration; March 29, 2019. 5. Apex Biologix. Data on file, DOC-0004, June 2025.
StimRouter is a registered trademark and TalisMann is a trademark of Bioness, Inc. GELSYN-3, and DUROLANE are registered trademarks and StimTrial is a trademark of Bioventus LLC. SUPARTZ FX is a registered trademark of Seikagaku Corp.





